Comparative 1-substituted imidazole inhibition of cytochrome p450 isozyme-selective activities in human and mouse hepatic microsomes.

Franklin MR and Constance JE (2007). Drug Metab Rev, 39(2-3), 309-22.

 

Xenobiotic metabolism of plant secondary compounds in oak (Quercus agrifolia) by specialist and generalist woodrat herbivores, genus.

Haley SL, Lamb JG, Franklin MR, Constance JE, Dearing MD (2007). Neotoma. J Chem Ecol, 33(11), 2111-22.
 

Xenobiotic metabolism of plant secondary compounds in juniper (Juniperus monosperma) by specialist and generalist woodrat herbivores, genus Neotoma.

Haley SL, Lamb JG, Franklin MR, Constance JE, Denise Dearing M (2007). Comp Biochem Physiol C Toxicol Pharmacol, 146(4), 552-60.
 

"Pharm-ecology" of diet shifting: biotransformation of plant secondary compounds in creosote (Larrea tridentata) by a woodrat herbivore, Neotoma lepida.

Haley SL, Lamb JG, Franklin MR, Constance JE, Dearing MD (2008). Physiol Biochem Zool, 81(5), 584-93.
 

Controlling subcellular localization to alter function: Sending oncogenic Bcr-Abl to the nucleus causes apoptosis.

Dixon AS, Kakar M, Schneider KM, Constance JE, Paullin BC, Lim CS (2009). J Control Release, 140(3), 245-9.
 

A once-per-day, drug-in-food protocol for prolonged administration of antiepileptic drugs in animal models.

Ali A, Dua Y, Constance JE, Franklin MR, Dudek FE (2012). Epilepsia, 53(1), 199-206.
 

Improved coiled-coil design enhances interaction with Bcr-Abl and induces apoptosis.

Dixon AS, Miller GD, Bruno BJ, Constance JE, Woessner DW, Fidler TP, Robertson JC, Cheatham TE 3rd, Lim CS (2012). Mol Pharm, 9(1), 187-95.
 

Targeting malignant mitochondria with therapeutic peptides. [Review].

Constance JE, Lim CS (2012). Ther Deliv, 3(8), 961-79.
 

Changing the subcellular location of the oncoprotein Bcr-Abl using rationally designed capture motifs.

Dixon AS, Constance JE, Tanaka T, Rabbitts TH, Lim CS (2012). Pharm Res, 29(4), 1098-109.
 

Correction to "improved coiled-coil design enhances interaction with bcr-abl and induces apoptosis".

Dixon AS, Miller GD, Bruno BJ, Constance JE, Woessner DW, Fidler TP, Robertson JC, Cheatham TE 3rd, Lim CS (2012). Mol Pharm, 9(5), 1535.
 

Direct induction of apoptosis using an optimal mitochondrially targeted p53.

Mossalam M, Matissek KJ, Okal A, Constance JE, Lim CS (2012). Mol Pharm, 9(5), 1449-58.
 

Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells.

Constance JE, Despres SD, Nishida A, Lim CS (2012). Pharm Res, 29(8), 2317-28.
 

Enhanced and selective killing of chronic myelogenous leukemia cells with an engineered BCR-ABL binding protein and imatinib.

Constance JE, Woessner DW, Matissek KJ, Mossalam M, Lim CS (2012). Mol Pharm, 9(11), 3318-29.
 

Characteristics and publication patterns of obstetric studies registered in ClinicalTrials.gov.

Stockmann C, Sherwin CM, Koren G, Campbell SC, Constance JE, Linakis M, Balch A, Varner MW, Spigarelli MG (2014). J Clin Pharmacol, 54(4), 432-7.
 

Pharmacokinetics and pharmacodynamics of antifungals in children and their clinical implications. [Review].

Stockmann C, Constance JE, Roberts JK, Olson J, Doby EH, Ampofo K, Stiers J, Spigarelli MG, Sherwin CM (2014). Clin Pharmacokinet, 53(5), 429-54.
 

Vancomycin pharmacokinetic models: informing the clinical management of drug-resistant bacterial infections. [Review].

Stockmann C, Roberts JK, Yu T, Constance JE, Knibbe CA, Spigarelli MG, Sherwin CM (2014). Expert Rev Anti Infect Ther, 12(11), 1371-88.
 

Pharmacokinetics and pharmacodynamics of antibacterials, antifungals, and antivirals used most frequently in neonates and infants.

Roberts JK, Stockmann C, Constance JE, Stiers J, Spigarelli MG, Ward RM, Sherwin CM (2014). Clin Pharmacokinet, 53(7), 581-610.
 

Considerations in the pharmacologic treatment and prevention of neonatal sepsis. [Review].

Stockmann C, Spigarelli MG, Campbell SC, Constance JE, Courter JD, Thorell EA, Olson J, Sherwin CM (2014). Paediatr Drugs, 16(1), 67-81.
 

Epidemiological Evaluation of Blood Culture Patterns among Neonates Receiving Vancomycin.

Yakub SY, Constance JE, Stockmann C, Linakis M, Campbell SC, Sherwin CM, Korgenski EK, Balch A, Spigarelli MG (2014). Indian J Microbiol, 54(4), 389-95.
 

An extensive pharmacokinetic, metabolic and toxicological review of elderly patients under intensive chemotherapy for acute myeloid leukemia.

Kaur I, Constance JE, Kosak KM, Spigarelli MG, Sherwin CM (2015). Expert Opin Drug Metabol Toxicol, 11(1), 53-65.
 

Pediatric vancomycin dosing: Trends over time and the impact of therapeutic drug monitoring.

Balch AH, Constance JE, Thorell EA, Stockmann C, Korgenski EK, Campbell SC, Spigarelli MG, Sherwin CM (2015). J Clin Pharmacol, 55(2), 212-20.
 

Special population considerations and regulatory affairs for clinical research.

Grimsrud K, Sherwin CM, Constance JE, Tak C, Zuppa AF, Spigarelli MG, Mihalopoulos NL (2015). Clin Res Regul Aff, 32(2), 47-56.
 

A propensity matched cohort study of vancomycin-associated nephrotoxicity in neonates.

Constance JE, Balch A, Stockmann CS, Linakis MW, Korgenski EK, Roberts J, Ward RM, Sherwin CM, Spigarelli MG. (2015) Arch Dis Child Fetal Neonatal Ed, 101(3):F236-43.
 

Renal function descriptors in neonates: Which creatinine-based formula best describes vancomycin clearance?

Bhongsatiern J, Stockmann C, Yu T, Moorthy G, Constance JE, Spigarelli MG, Desai PB, Sherwin CM. (2015) J Clin Pharmacol, 56(5):528-40
 

Pharmacokinetic considerations in the use of antivirals in neonates.

Enioutina E, Constance JE, Stockmann C, Linakis M, Yu T, Rower J, Balch A, Sherwin CM, Spigarelli MG. (2015) Expert Opin Drug Metab Toxicol, 11(12), 1861-78.
 

Pharmacodynamic studies of voriconazole: informing the clinical management of invasive fungal infections. [Review]

Job KM, Olson J, Stockmann C, Constance JE, Enioutina EY, Rower JE, Linakis MW, Balch AH, Yu T, Liu X, Thorell EA, Sherwin CM. (2016) Expert Rev Anti Infect Ther, 14(8):731-46.
 

Unanswered questions regarding optimal pediatric vancomycin use.

Stockmann C, Sammons H, Starkey E, Constance JE, Sherwin CM (2016) Therapeutic Drug Monitoring, 38(3):419-20
 

Herbal medicines: challenges in the modern world. Part 4. Canada and United States.

Job KM, Kiang TK, Constance JE, Sherwin CM, Enioutina EY (2016) Expert Rev Clin Pharmacol, 3:1-13.
 

Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin.

Constance JE, Reith D, Ward RM, Balch A, Stockmann C, Korgenski EK, Thorell EA, Sherwin CM (2017) J Perinatol, 37(10):1093-1102
 

Pharmacokinetics, pharmacodynamics and pharmacogenetics associated with nonsteroidal anti-inflammatory drugs and opioids in pediatric cancer patients. [Review]

Constance JE, Campbell SC, Somani AA, Yellepeddi V, Owens KH, Sherwin CM (2017) Expert Opin Drug Metab Toxicol, 13(7):715-724.
 

Supportive Care Medications Coinciding With Chemotherapy Among Children With Hematologic Malignancy.

Biltaji E, Enioutina EY, Yellepeddi V, Rower JE, Sherwin CMT, Ward RM, Lemons RS, Constance JE. (2020) Leuk Lymphoma (online ahead of print) PMID: 32264729
 

Dronabinol Prescribing and Exposure Among Children and Young Adults Diagnosed with Cancer. Journal of Adolescent and Young Adult Oncology.

Rower JE, King AD, Wilkins D, Wilkes J, Yellepeddi V, Maese L, Lemons RS, Constance JE. (2020) (Online ahead of print) PMID: 32678694
 

Predicting Resolvin D1 Pharmacokinetics in Humans with Physiologically Based Pharmacokinetic Modeling.

Yellepeddi V, Parashar K, Dean S, Watt K, Constance JE, Baker O. (2020) Clin Transl Sci. (online ahead of print) PMID: 33202089